What's new in Endnote 20 video
IMPORTANT:
EndNote 20 (and Endnote X9.3 and later) use a different (64 bit) database engine from EndNote X9.2 and earlier versions. This means that EndNote X9.3.3 and Endnote 20 library files are not backward compatible. (You cannot open an EN20 library in ENX9.1 or X9.2)
EndNote libraries created in EndNote X9.2 and earlier CAN be converted into libraries openable by EndNote X9.3.3 or Endnote 20.
A full explanation of this change and some trouble shooting instructions can be found here on the Clarivate Support website.